TY - JOUR
T1 - A tomographic UV-sheet scanning technique for producing 3D fluorescence images of x-ray beams in a radio-fluorogenic gel
AU - Yao, Tiantian
AU - Gasparini, Alessia
AU - de Haas, Thijs
AU - Luthjens, Lee
AU - Denkova, Antonia
AU - Warman, John
PY - 2017/4/11
Y1 - 2017/4/11
N2 - In this work a 40 mm cube of an optically clear, radio-fluorogenic gel composed of partially-polymerized tertiary-butyl acrylate and maleimido-pyrene (~0.01%) is irradiated with orthogonally-crossed, 10 mm square and round, 200 kVp x-ray beams. A thin sheet of UV light is produced between two parallel plates with 2 mm slits illuminated by collimated, linear-array, LED sources. The gel is transported 1 mm at a time through the UV sheet and the fluorescence from the emissive, polymeric radiolytic product formed in the x-ray tracks is recorded, as both JPEG and raw-DNG files, using a CCD camera placed orthogonal to the plane of the excitation light. The resulting stack of 40 tomographic slices are imported into freely-available software to produce 3D animated images of the radiation-induced fluorescence.
AB - In this work a 40 mm cube of an optically clear, radio-fluorogenic gel composed of partially-polymerized tertiary-butyl acrylate and maleimido-pyrene (~0.01%) is irradiated with orthogonally-crossed, 10 mm square and round, 200 kVp x-ray beams. A thin sheet of UV light is produced between two parallel plates with 2 mm slits illuminated by collimated, linear-array, LED sources. The gel is transported 1 mm at a time through the UV sheet and the fluorescence from the emissive, polymeric radiolytic product formed in the x-ray tracks is recorded, as both JPEG and raw-DNG files, using a CCD camera placed orthogonal to the plane of the excitation light. The resulting stack of 40 tomographic slices are imported into freely-available software to produce 3D animated images of the radiation-induced fluorescence.
UR - http://resolver.tudelft.nl/uuid:8463a0df-b9a0-4dfd-ae7d-cdf77ef166ab
U2 - 10.1088/2057-1976/aa684b
DO - 10.1088/2057-1976/aa684b
M3 - Article
SN - 2057-1976
VL - 3
JO - Biomedical Physics & Engineering Express
JF - Biomedical Physics & Engineering Express
IS - 2
ER -