Analysis of Motility in Apparently Normal Small Bowel–Relationship to Crohn’s Symptoms

R Gollifer; A Menys; J Makanyanga; C Puylaert; Frans Vos; Jaap Stoker; D Atkinson; Stuart A. Taylor

Analysis of Motility in Apparently Normal Small Bowel–Relationship to Crohn’s Symptoms

R Gollifer, A Menys, J Makanyanga, C Puylaert, Frans Vos, Jaap Stoker, D Atkinson, Stuart A. Taylor

Research output: Chapter in Book/Conference proceedings/Edited volume › Conference contribution › Scientific › peer-review

Abstract

Crohn’s disease (CD) patients often suffer abdominal symptoms even when their disease is apparently in remission with no identifiable active inflammation.1 Ongoing aberrant gut motility has been postulated as a cause, and this can now be quantified using MRI.2 This study tested the association between abdominal symptoms based on the Harvey-Bradshaw Index (HBI) and MRI derived motility metrics in morphologically healthy small bowel in CD patients. An inverse association was found between reduced motility spatial variation across the small bowel and symptoms, particularly diarrhoea. This association was strongest when HBI scores were higher.

Original language	English
Title of host publication	Proceedings of the ISMRM Annual Meeting & Exhibition 2017
Publisher	ISMRM
Pages	4967-4967
Publication status	Published - 7 Apr 2017
Event	ISMRM (International Society for Magnetic Resonance in Medicine) Annual Meeting & Exhibition - Honolulu, United States Duration: 22 Apr 2017 → 27 Apr 2017 Conference number: 25

Conference

Conference	ISMRM (International Society for Magnetic Resonance in Medicine) Annual Meeting & Exhibition
Country/Territory	United States
City	Honolulu
Period	22/04/17 → 27/04/17

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

@inproceedings{79cc9dec7fbb446da7d896d7616630fd,

title = "Analysis of Motility in Apparently Normal Small Bowel–Relationship to Crohn{\textquoteright}s Symptoms",

abstract = "Crohn{\textquoteright}s disease (CD) patients often suffer abdominal symptoms even when their disease is apparently in remission with no identifiable active inflammation.1 Ongoing aberrant gut motility has been postulated as a cause, and this can now be quantified using MRI.2 This study tested the association between abdominal symptoms based on the Harvey-Bradshaw Index (HBI) and MRI derived motility metrics in morphologically healthy small bowel in CD patients. An inverse association was found between reduced motility spatial variation across the small bowel and symptoms, particularly diarrhoea. This association was strongest when HBI scores were higher.",

author = "R Gollifer and A Menys and J Makanyanga and C Puylaert and Frans Vos and Jaap Stoker and D Atkinson and Taylor, {Stuart A.}",

year = "2017",

month = apr,

day = "7",

language = "English",

pages = "4967--4967",

booktitle = "Proceedings of the ISMRM Annual Meeting & Exhibition 2017",

publisher = "ISMRM",

note = "ISMRM (International Society for Magnetic Resonance in Medicine) Annual Meeting & Exhibition ; Conference date: 22-04-2017 Through 27-04-2017",

}

Gollifer, R, Menys, A, Makanyanga, J, Puylaert, C, Vos, F, Stoker, J, Atkinson, D & Taylor, SA 2017, Analysis of Motility in Apparently Normal Small Bowel–Relationship to Crohn’s Symptoms. in Proceedings of the ISMRM Annual Meeting & Exhibition 2017. ISMRM, pp. 4967-4967, ISMRM (International Society for Magnetic Resonance in Medicine) Annual Meeting & Exhibition, Honolulu, United States, 22/04/17.

TY - GEN

T1 - Analysis of Motility in Apparently Normal Small Bowel–Relationship to Crohn’s Symptoms

AU - Gollifer, R

AU - Menys, A

AU - Makanyanga, J

AU - Puylaert, C

AU - Vos, Frans

AU - Stoker, Jaap

AU - Atkinson, D

AU - Taylor, Stuart A.

N1 - Conference code: 25

PY - 2017/4/7

Y1 - 2017/4/7

N2 - Crohn’s disease (CD) patients often suffer abdominal symptoms even when their disease is apparently in remission with no identifiable active inflammation.1 Ongoing aberrant gut motility has been postulated as a cause, and this can now be quantified using MRI.2 This study tested the association between abdominal symptoms based on the Harvey-Bradshaw Index (HBI) and MRI derived motility metrics in morphologically healthy small bowel in CD patients. An inverse association was found between reduced motility spatial variation across the small bowel and symptoms, particularly diarrhoea. This association was strongest when HBI scores were higher.

AB - Crohn’s disease (CD) patients often suffer abdominal symptoms even when their disease is apparently in remission with no identifiable active inflammation.1 Ongoing aberrant gut motility has been postulated as a cause, and this can now be quantified using MRI.2 This study tested the association between abdominal symptoms based on the Harvey-Bradshaw Index (HBI) and MRI derived motility metrics in morphologically healthy small bowel in CD patients. An inverse association was found between reduced motility spatial variation across the small bowel and symptoms, particularly diarrhoea. This association was strongest when HBI scores were higher.

UR - https://dev.ismrm.org/2017/4967.html

M3 - Conference contribution

SP - 4967

EP - 4967

BT - Proceedings of the ISMRM Annual Meeting & Exhibition 2017

PB - ISMRM

T2 - ISMRM (International Society for Magnetic Resonance in Medicine) Annual Meeting & Exhibition

Y2 - 22 April 2017 through 27 April 2017

ER -

Analysis of Motility in Apparently Normal Small Bowel–Relationship to Crohn’s Symptoms

Abstract

Conference

UN SDGs

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