Biocatalysis explained: From pharmaceutical to bulk chemical production

Eman M.M. Abdelraheem; Hanna Busch; Ulf Hanefeld; Fabio Tonin

doi:10.1039/c9re00301k

Biocatalysis explained: From pharmaceutical to bulk chemical production

Eman M.M. Abdelraheem, Hanna Busch, Ulf Hanefeld^*, Fabio Tonin

^*Corresponding author for this work

BT/Biocatalysis

Research output: Contribution to journal › Review article › peer-review

79 Citations (Scopus)

186 Downloads (Pure)

Abstract

Biocatalysis is one of the most promising technologies for the sustainable synthesis of molecules for pharmaceutical, biotechnological and industrial purposes. From the gram to the ton scale, biocatalysis is employed with success. This is underpinned by the fact that the global enzyme market is predicted to increase from $7 billion to $10 billion by 2024. This review concentrates on showing the strong benefits that biocatalysis and the use of enzymes can provide to synthetic chemistry. Several examples of successful implementations of enzymes are discussed highlighting not only high-value pharmaceutical processes but also low-cost bulk products. Thus, biocatalytic methods make the chemistry more environmentally friendly and product specific.

Original language	English
Pages (from-to)	1878-1894
Journal	Reaction Chemistry and Engineering
Volume	4
Issue number	11
DOIs	https://doi.org/10.1039/c9re00301k
Publication status	Published - 2019

Access to Document

10.1039/c9re00301k

c9re00301kFinal published version, 2.42 MBLicence: CC BY

Cite this

@article{cf9951d5758a4ad3a42f49f481601b95,

title = "Biocatalysis explained: From pharmaceutical to bulk chemical production",

abstract = "Biocatalysis is one of the most promising technologies for the sustainable synthesis of molecules for pharmaceutical, biotechnological and industrial purposes. From the gram to the ton scale, biocatalysis is employed with success. This is underpinned by the fact that the global enzyme market is predicted to increase from $7 billion to $10 billion by 2024. This review concentrates on showing the strong benefits that biocatalysis and the use of enzymes can provide to synthetic chemistry. Several examples of successful implementations of enzymes are discussed highlighting not only high-value pharmaceutical processes but also low-cost bulk products. Thus, biocatalytic methods make the chemistry more environmentally friendly and product specific.",

author = "Abdelraheem, {Eman M.M.} and Hanna Busch and Ulf Hanefeld and Fabio Tonin",

year = "2019",

doi = "10.1039/c9re00301k",

language = "English",

volume = "4",

pages = "1878--1894",

journal = "Reaction Chemistry and Engineering",

issn = "2058-9883",

publisher = "Royal Society of Chemistry",

number = "11",

}

TY - JOUR

T1 - Biocatalysis explained

T2 - From pharmaceutical to bulk chemical production

AU - Abdelraheem, Eman M.M.

AU - Busch, Hanna

AU - Hanefeld, Ulf

AU - Tonin, Fabio

PY - 2019

Y1 - 2019

N2 - Biocatalysis is one of the most promising technologies for the sustainable synthesis of molecules for pharmaceutical, biotechnological and industrial purposes. From the gram to the ton scale, biocatalysis is employed with success. This is underpinned by the fact that the global enzyme market is predicted to increase from $7 billion to $10 billion by 2024. This review concentrates on showing the strong benefits that biocatalysis and the use of enzymes can provide to synthetic chemistry. Several examples of successful implementations of enzymes are discussed highlighting not only high-value pharmaceutical processes but also low-cost bulk products. Thus, biocatalytic methods make the chemistry more environmentally friendly and product specific.

AB - Biocatalysis is one of the most promising technologies for the sustainable synthesis of molecules for pharmaceutical, biotechnological and industrial purposes. From the gram to the ton scale, biocatalysis is employed with success. This is underpinned by the fact that the global enzyme market is predicted to increase from $7 billion to $10 billion by 2024. This review concentrates on showing the strong benefits that biocatalysis and the use of enzymes can provide to synthetic chemistry. Several examples of successful implementations of enzymes are discussed highlighting not only high-value pharmaceutical processes but also low-cost bulk products. Thus, biocatalytic methods make the chemistry more environmentally friendly and product specific.

UR - http://www.scopus.com/inward/record.url?scp=85073759228&partnerID=8YFLogxK

U2 - 10.1039/c9re00301k

DO - 10.1039/c9re00301k

M3 - Review article

AN - SCOPUS:85073759228

SN - 2058-9883

VL - 4

SP - 1878

EP - 1894

JO - Reaction Chemistry and Engineering

JF - Reaction Chemistry and Engineering

IS - 11

ER -

Biocatalysis explained: From pharmaceutical to bulk chemical production

Abstract

Access to Document

Other files and links

Fingerprint

Cite this