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Biodegradation and mechanical behavior of an advanced bioceramic-containing Mg matrix composite synthesized through in-situ solid-state oxidation. / Naddaf Dezfuli, Sina; Brouwer, J. C.; Mol, J. M.C.; van der Helm, F. C.T.; Zhou, J.

In: Journal of the Mechanical Behavior of Biomedical Materials, Vol. 80, 2018, p. 209-221.

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@article{7b88ee07366a4289936524c410412313,
title = "Biodegradation and mechanical behavior of an advanced bioceramic-containing Mg matrix composite synthesized through in-situ solid-state oxidation",
abstract = "Recent studies have shown great potential of Mg matrix composites for biodegradable orthopedic devices. However, the poor structural integrity of these composites, which results in excessive localized corrosion and premature mechanical failure, has hindered their widespread applications. In this research, an in-situ Powder Metallurgy (PM) method was used to fabricate a novel biodegradable Mg-bredigite composite and to achieve enhanced chemical interfacial locking between the constituents by triggering a solid-state thermochemical reaction between Mg and bredigite particles. The reaction resulted in a highly densified and integrated microstructure, which prevented corrosion pits from propagating when the composite was immersed in a physiological solution. In addition, chemical interlocking between the constituents prohibited interparticle fracture and subsequent surface delamination during compression testing, enabling the composite to withstand larger plastic deformation before mechanical failure. Furthermore, the composite was proven to be biocompatible and capable of maintaining its ultimate compressive strength in the strength range of cortical bone after 25-day immersion in DMEM. The research provided the necessary information to guide further research towards the development of a next generation of biodegradable Mg matrix composites with enhanced chemical interlocking.",
keywords = "Biocompatibility, Chemical interlocking, Composite, Degradation, Magnesium, Mechanical property",
author = "{Naddaf Dezfuli}, Sina and Brouwer, {J. C.} and Mol, {J. M.C.} and {van der Helm}, {F. C.T.} and J. Zhou",
year = "2018",
doi = "10.1016/j.jmbbm.2018.01.014",
language = "English",
volume = "80",
pages = "209--221",
journal = "Journal of the Mechanical Behavior of Biomedical Materials",
issn = "1751-6161",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Biodegradation and mechanical behavior of an advanced bioceramic-containing Mg matrix composite synthesized through in-situ solid-state oxidation

AU - Naddaf Dezfuli, Sina

AU - Brouwer, J. C.

AU - Mol, J. M.C.

AU - van der Helm, F. C.T.

AU - Zhou, J.

PY - 2018

Y1 - 2018

N2 - Recent studies have shown great potential of Mg matrix composites for biodegradable orthopedic devices. However, the poor structural integrity of these composites, which results in excessive localized corrosion and premature mechanical failure, has hindered their widespread applications. In this research, an in-situ Powder Metallurgy (PM) method was used to fabricate a novel biodegradable Mg-bredigite composite and to achieve enhanced chemical interfacial locking between the constituents by triggering a solid-state thermochemical reaction between Mg and bredigite particles. The reaction resulted in a highly densified and integrated microstructure, which prevented corrosion pits from propagating when the composite was immersed in a physiological solution. In addition, chemical interlocking between the constituents prohibited interparticle fracture and subsequent surface delamination during compression testing, enabling the composite to withstand larger plastic deformation before mechanical failure. Furthermore, the composite was proven to be biocompatible and capable of maintaining its ultimate compressive strength in the strength range of cortical bone after 25-day immersion in DMEM. The research provided the necessary information to guide further research towards the development of a next generation of biodegradable Mg matrix composites with enhanced chemical interlocking.

AB - Recent studies have shown great potential of Mg matrix composites for biodegradable orthopedic devices. However, the poor structural integrity of these composites, which results in excessive localized corrosion and premature mechanical failure, has hindered their widespread applications. In this research, an in-situ Powder Metallurgy (PM) method was used to fabricate a novel biodegradable Mg-bredigite composite and to achieve enhanced chemical interfacial locking between the constituents by triggering a solid-state thermochemical reaction between Mg and bredigite particles. The reaction resulted in a highly densified and integrated microstructure, which prevented corrosion pits from propagating when the composite was immersed in a physiological solution. In addition, chemical interlocking between the constituents prohibited interparticle fracture and subsequent surface delamination during compression testing, enabling the composite to withstand larger plastic deformation before mechanical failure. Furthermore, the composite was proven to be biocompatible and capable of maintaining its ultimate compressive strength in the strength range of cortical bone after 25-day immersion in DMEM. The research provided the necessary information to guide further research towards the development of a next generation of biodegradable Mg matrix composites with enhanced chemical interlocking.

KW - Biocompatibility

KW - Chemical interlocking

KW - Composite

KW - Degradation

KW - Magnesium

KW - Mechanical property

UR - http://www.scopus.com/inward/record.url?scp=85041551860&partnerID=8YFLogxK

U2 - 10.1016/j.jmbbm.2018.01.014

DO - 10.1016/j.jmbbm.2018.01.014

M3 - Article

VL - 80

SP - 209

EP - 221

JO - Journal of the Mechanical Behavior of Biomedical Materials

T2 - Journal of the Mechanical Behavior of Biomedical Materials

JF - Journal of the Mechanical Behavior of Biomedical Materials

SN - 1751-6161

ER -

ID: 40075973