TY - JOUR
T1 - Electrochemical Selective and Simultaneous Detection of Diclofenac and Ibuprofen in Aqueous Solution Using HKUST-1 Metal-Organic Framework-Carbon Nanofiber Composite Electrode
AU - Motoc, Sorina
AU - Manea, Florica
AU - Iacob, Adriana
AU - Martinez-Joaristi, Alberto
AU - Gascon, J.
AU - Pop, Aniela
AU - Schoonman, Joop
PY - 2016/10/17
Y1 - 2016/10/17
N2 - In this study, the detection protocols for the individual, selective, and simultaneous determination of ibuprofen (IBP) and diclofenac (DCF) in aqueous solutions have been developed using HKUST-1 metal-organic framework-carbon nanofiber composite (HKUST-CNF) electrode. The morphological and electrical characterization of modified composite electrode prepared by film casting was studied by scanning electronic microscopy and four-point-probe methods. The electrochemical characterization of the electrode by cyclic voltammetry (CV) was considered the reference basis for the optimization of the operating conditions for chronoamperometry (CA) and multiple-pulsed amperometry (MPA). This electrode exhibited the possibility to selectively detect IBP and DCF by simple switching the detection potential using CA. However, the MPA operated under optimum working conditions of four potential levels selected based on CV shape in relation to the potential value, pulse time, and potential level number, and order allowed the selective/simultaneous detection of IBP and DCF characterized by the enhanced detection performance. For this application, the HKUST-CNF electrode exhibited a good stability and reproducibility of the results was achieved.
AB - In this study, the detection protocols for the individual, selective, and simultaneous determination of ibuprofen (IBP) and diclofenac (DCF) in aqueous solutions have been developed using HKUST-1 metal-organic framework-carbon nanofiber composite (HKUST-CNF) electrode. The morphological and electrical characterization of modified composite electrode prepared by film casting was studied by scanning electronic microscopy and four-point-probe methods. The electrochemical characterization of the electrode by cyclic voltammetry (CV) was considered the reference basis for the optimization of the operating conditions for chronoamperometry (CA) and multiple-pulsed amperometry (MPA). This electrode exhibited the possibility to selectively detect IBP and DCF by simple switching the detection potential using CA. However, the MPA operated under optimum working conditions of four potential levels selected based on CV shape in relation to the potential value, pulse time, and potential level number, and order allowed the selective/simultaneous detection of IBP and DCF characterized by the enhanced detection performance. For this application, the HKUST-CNF electrode exhibited a good stability and reproducibility of the results was achieved.
KW - Chronoamperometry
KW - Cyclic voltammetry
KW - Diclofenac
KW - Electrochemical selective and simultaneous detection
KW - Ibuprofen
KW - Metal-organic framework-carbon nanofiber composite electrode
KW - Multiple-pulsed amperometry
UR - http://resolver.tudelft.nl/uuid:51d08c0b-f457-42ea-bceb-4c1ce75aed34
UR - http://www.scopus.com/inward/record.url?scp=84991829480&partnerID=8YFLogxK
U2 - 10.3390/s16101719
DO - 10.3390/s16101719
M3 - Article
AN - SCOPUS:84991829480
SN - 1424-8220
VL - 16
JO - Sensors
JF - Sensors
IS - 10
M1 - 1719
ER -