• Xueqiu Jian
  • Claudia L. Satizabal
  • Albert V. Smith
  • Katharina Wittfeld
  • Joshua C. Bis
  • Fang-Chi Hsu
  • Kwangsik Nho
  • Shuo Li
  • Wiro J. Niessen
  • More Authors
White matter hyperintensities (WMH) on brain magnetic resonance imaging are typical signs of cerebral small vessel disease and may indicate various preclinical, age-related neurological disorders, such as stroke. Though WMH are highly heritable, known common variants explain a small proportion of the WMH variance. The contribution of low-frequency/rare coding variants to WMH burden has not been explored.
Original languageEnglish
Pages (from-to)1812-1819
JournalStroke
Volume49
Issue number8
DOIs
Publication statusPublished - 2018

    Research areas

  • cerebral small vessel disease, exome, magnetic resonance imaging, meta-analysis, white matter

ID: 47148881