TY - JOUR
T1 - Fibroepithelioma of Pinkus (FeP) located in the left lower quadrant of the abdomen - Case Report and review of the literature
AU - Mihai, Mara Madalina
AU - Voicu, Cristiana
AU - Lupu, Mihai
AU - Koleva, Nely
AU - Patterson, James W.
AU - Lotti, Torello
AU - Lotti, Jacopo
AU - França, Katlein
AU - Batashki, Atanas
AU - Bakardzhiev, Ilko
AU - Wollina, Uwe
AU - Tchernev, Georgi
PY - 2017
Y1 - 2017
N2 - Background: Fibroepithelioma of Pinkus (FeP) is an uncommon and controversial skin lesion, sharing features of both basal cell carcinoma (BCC) and trichoepithelioma. In this article, we present a case of FeP and synthesise current concepts on the etiopathogenesis, diagnosis and treatment of this uncommon tumour. Case Report: We report the case of an 88-year-old male patient presenting to the dermatology clinic for a sharply demarcated, pink, exophytic cutaneous tumour situated in the left inguinal region. The histopathological examination performed after complete surgical excision of the lesion revealed a diagnosis of FeP. A systematic review of the literature was conducted. The terms 'fibroepithelioma' and 'Pinkus' have been searched in bibliographical databases, including PubMed and Google Scholar, without time limitation up to February 15th, 2017. Seventy-nine articles that fulfilled all the required conditions were identified. Relevant citations and additional articles identified from references have been assessed. The systematic review included a total number of 452 cases of FeP. Conclusion: Even though FeP is considered a relatively rare tumour, its true incidence rate might be higher than previously believed. The clinical aspects of the lesion described in this paper and its location in the left lower quadrant of the abdomen are classic features of FeP. Histopathologic examination revealed features of both BCC and trichoepithelioma. Further epidemiological studies are required to clarify whether patients with FEP should be screened for the occurrence of other malignancies.
AB - Background: Fibroepithelioma of Pinkus (FeP) is an uncommon and controversial skin lesion, sharing features of both basal cell carcinoma (BCC) and trichoepithelioma. In this article, we present a case of FeP and synthesise current concepts on the etiopathogenesis, diagnosis and treatment of this uncommon tumour. Case Report: We report the case of an 88-year-old male patient presenting to the dermatology clinic for a sharply demarcated, pink, exophytic cutaneous tumour situated in the left inguinal region. The histopathological examination performed after complete surgical excision of the lesion revealed a diagnosis of FeP. A systematic review of the literature was conducted. The terms 'fibroepithelioma' and 'Pinkus' have been searched in bibliographical databases, including PubMed and Google Scholar, without time limitation up to February 15th, 2017. Seventy-nine articles that fulfilled all the required conditions were identified. Relevant citations and additional articles identified from references have been assessed. The systematic review included a total number of 452 cases of FeP. Conclusion: Even though FeP is considered a relatively rare tumour, its true incidence rate might be higher than previously believed. The clinical aspects of the lesion described in this paper and its location in the left lower quadrant of the abdomen are classic features of FeP. Histopathologic examination revealed features of both BCC and trichoepithelioma. Further epidemiological studies are required to clarify whether patients with FEP should be screened for the occurrence of other malignancies.
KW - Basal cell carcinoma
KW - Fibroepithelioma of Pinkus
KW - Trichoblastoma
KW - Trichoepithelioma
UR - http://resolver.tudelft.nl/uuid:fa64da3c-1bf0-45ca-b126-376514b5f1b9
UR - http://www.scopus.com/inward/record.url?scp=85027412574&partnerID=8YFLogxK
U2 - 10.3889/oamjms.2017.079
DO - 10.3889/oamjms.2017.079
M3 - Review article
AN - SCOPUS:85027412574
SN - 1857-9655
VL - 5
SP - 439
EP - 444
JO - Open Access Macedonian Journal of Medical Sciences
JF - Open Access Macedonian Journal of Medical Sciences
IS - 4 Special Issue GlobalDermatology
ER -