Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging

Tianshi Wang*, Tom Pfeiffer, Joost Daemen, Frits Mastik, Wolfgang Wieser, A. F.W. Van Der Steen, Robert Huber, Gijs Van Soest

*Corresponding author for this work

    Research output: Contribution to journalConference articleScientificpeer-review

    Abstract

    We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.

    Original languageEnglish
    Article number1085503
    Number of pages6
    JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
    Volume10855
    DOIs
    Publication statusPublished - 2019
    EventDiagnostic and Therapeutic Applications of Light in Cardiology 2019 - San Francisco, United States
    Duration: 2 Feb 20193 Feb 2019

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