Abstract
The attenuation coefficient (AC) is a tissue property that can be estimated from optical coherence tomography (OCT) data. We observed that excessive noise below the retina might cause both an underestimation and a significant variation of the estimated AC values by a state-of-the-art algorithm. Two methods were proposed to reduce these effects: I) by removing the average noise signal from the OCT data; II) by excluding the detected noise region below the retina. The methods were applied to four circular peripapillary retinal scans of a healthy subject. We evaluated all methods quantitatively using metrics for the inter- and intra-A-lines variation of the estimated ACs. Both methods resulted in higher ACs thereby reducing the bias. However, only method II succeeded in reducing the amount of variation by both metrics; method I made things worse. In conclusion, method II yields a more robust and more precise estimate of the AC, in particular for the choroid and sclera, compared to the baseline method.
Original language | English |
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Title of host publication | 2016 IEEE International Symposium on Biomedical Imaging: From Nano to Macro |
Publisher | IEEE |
Pages | 706-709 |
Number of pages | 4 |
ISBN (Print) | 978-1-4799-2350-2 |
DOIs | |
Publication status | Published - 2016 |
Event | 2016 IEEE 13th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2016 - Prague, Czech Republic Duration: 13 Apr 2016 → 16 Apr 2016 |
Conference
Conference | 2016 IEEE 13th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2016 |
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Country/Territory | Czech Republic |
City | Prague |
Period | 13/04/16 → 16/04/16 |