@inproceedings{7fd5f68e254349cc8cce5b9bc2796c66,
title = "Nonrigid image registration using multi-scale 3D convolutional neural networks",
abstract = "In this paper we propose a method to solve nonrigid image registration through a learning approach, instead of via iterative optimization of a predefined dissimilarity metric. We design a Convolutional Neural Network (CNN) architecture that, in contrast to all other work, directly estimates the displacement vector field (DVF) from a pair of input images. The proposed RegNet is trained using a large set of artificially generated DVFs, does not explicitly define a dissimilarity metric, and integrates image content at multiple scales to equip the network with contextual information. At testing time nonrigid registration is performed in a single shot, in contrast to current iterative methods. We tested RegNet on 3D chest CT follow-up data. The results show that the accuracy of RegNet is on par with a conventional B-spline registration, for anatomy within the capture range. Training RegNet with artificially generated DVFs is therefore a promising approach for obtaining good results on real clinical data, thereby greatly simplifying the training problem. Deformable image registration can therefore be successfully casted as a learning problem.",
keywords = "Chest CT, Convolutional neural networks, Image registration, Multi-scale analysis",
author = "Hessam Sokooti and {De Vos}, {Bob D.} and Floris Berendsen and Boudewijn Lelieveldt and Ivana I{\v s}gum and Marius Staring",
year = "2017",
doi = "10.1007/978-3-319-66182-7_27",
language = "English",
isbn = "978-3-319-66181-0",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer",
pages = "232--239",
editor = "M. Descoteaux and L. Maier-Hein and A. Franz and P. Jannin and Collins, {D. Louis} and S. Duchesne",
booktitle = "Medical Image Computing and Computer Assisted Intervention - MICCAI 2017",
edition = "Part 1",
note = "Medical Image Computing and Computer-Assisted Intervention, MICCAI 2017 : 20th International Conference ; Conference date: 11-09-2017 Through 13-09-2017",
}