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Normative brain volumetry derived from different reference populations : impact on single-subject diagnostic assessment in dementia. / Vinke, Elisabeth J.; Huizinga, Wyke; Bergtholdt, Martin; Adams, Hieab H.; Steketee, Rebecca M.E.; Papma, Janne M.; De Jong, Frank Jan; Niessen, Wiro J.; Ikram, M. Arfan; More Authors.

In: Neurobiology of Aging, Vol. 84, 2019, p. 9-16.

Research output: Contribution to journalArticleScientificpeer-review

Harvard

Vinke, EJ, Huizinga, W, Bergtholdt, M, Adams, HH, Steketee, RME, Papma, JM, De Jong, FJ, Niessen, WJ, Ikram, MA & More Authors 2019, 'Normative brain volumetry derived from different reference populations: impact on single-subject diagnostic assessment in dementia' Neurobiology of Aging, vol. 84, pp. 9-16. https://doi.org/10.1016/j.neurobiolaging.2019.07.008

APA

Vinke, E. J., Huizinga, W., Bergtholdt, M., Adams, H. H., Steketee, R. M. E., Papma, J. M., ... More Authors (2019). Normative brain volumetry derived from different reference populations: impact on single-subject diagnostic assessment in dementia. Neurobiology of Aging, 84, 9-16. https://doi.org/10.1016/j.neurobiolaging.2019.07.008

Vancouver

Author

Vinke, Elisabeth J. ; Huizinga, Wyke ; Bergtholdt, Martin ; Adams, Hieab H. ; Steketee, Rebecca M.E. ; Papma, Janne M. ; De Jong, Frank Jan ; Niessen, Wiro J. ; Ikram, M. Arfan ; More Authors. / Normative brain volumetry derived from different reference populations : impact on single-subject diagnostic assessment in dementia. In: Neurobiology of Aging. 2019 ; Vol. 84. pp. 9-16.

BibTeX

@article{724f270c53c244c2a2c342805452b44d,
title = "Normative brain volumetry derived from different reference populations: impact on single-subject diagnostic assessment in dementia",
abstract = "Brain imaging data are increasingly made publicly accessible, and volumetric imaging measures derived from population-based cohorts may serve as normative data for individual patient diagnostic assessment. Yet, these normative cohorts are usually not a perfect reflection of a patient's base population, nor are imaging parameters such as field strength or scanner type similar. In this proof of principle study, we assessed differences between reference curves of subcortical structure volumes of normal controls derived from two population-based studies and a case-control study. We assessed the impact of any differences on individual assessment of brain structure volumes. Percentile curves were fitted on the three healthy cohorts. Next, percentile values for these subcortical structures for individual patients from these three cohorts, 91 mild cognitive impairment and 95 Alzheimer's disease cases and patients from the Alzheimer Center, were calculated, based on the distributions of each of the three cohorts. Overall, we found that the subcortical volume normative data from these cohorts are highly interchangeable, suggesting more flexibility in clinical implementation.",
keywords = "Imaging, MRI, Normative data, Subcortical brain volume",
author = "Vinke, {Elisabeth J.} and Wyke Huizinga and Martin Bergtholdt and Adams, {Hieab H.} and Steketee, {Rebecca M.E.} and Papma, {Janne M.} and {De Jong}, {Frank Jan} and Niessen, {Wiro J.} and Ikram, {M. Arfan} and {More Authors}",
year = "2019",
doi = "10.1016/j.neurobiolaging.2019.07.008",
language = "English",
volume = "84",
pages = "9--16",
journal = "Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology",
issn = "0197-4580",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Normative brain volumetry derived from different reference populations

T2 - Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology

AU - Vinke, Elisabeth J.

AU - Huizinga, Wyke

AU - Bergtholdt, Martin

AU - Adams, Hieab H.

AU - Steketee, Rebecca M.E.

AU - Papma, Janne M.

AU - De Jong, Frank Jan

AU - Niessen, Wiro J.

AU - Ikram, M. Arfan

AU - More Authors, null

PY - 2019

Y1 - 2019

N2 - Brain imaging data are increasingly made publicly accessible, and volumetric imaging measures derived from population-based cohorts may serve as normative data for individual patient diagnostic assessment. Yet, these normative cohorts are usually not a perfect reflection of a patient's base population, nor are imaging parameters such as field strength or scanner type similar. In this proof of principle study, we assessed differences between reference curves of subcortical structure volumes of normal controls derived from two population-based studies and a case-control study. We assessed the impact of any differences on individual assessment of brain structure volumes. Percentile curves were fitted on the three healthy cohorts. Next, percentile values for these subcortical structures for individual patients from these three cohorts, 91 mild cognitive impairment and 95 Alzheimer's disease cases and patients from the Alzheimer Center, were calculated, based on the distributions of each of the three cohorts. Overall, we found that the subcortical volume normative data from these cohorts are highly interchangeable, suggesting more flexibility in clinical implementation.

AB - Brain imaging data are increasingly made publicly accessible, and volumetric imaging measures derived from population-based cohorts may serve as normative data for individual patient diagnostic assessment. Yet, these normative cohorts are usually not a perfect reflection of a patient's base population, nor are imaging parameters such as field strength or scanner type similar. In this proof of principle study, we assessed differences between reference curves of subcortical structure volumes of normal controls derived from two population-based studies and a case-control study. We assessed the impact of any differences on individual assessment of brain structure volumes. Percentile curves were fitted on the three healthy cohorts. Next, percentile values for these subcortical structures for individual patients from these three cohorts, 91 mild cognitive impairment and 95 Alzheimer's disease cases and patients from the Alzheimer Center, were calculated, based on the distributions of each of the three cohorts. Overall, we found that the subcortical volume normative data from these cohorts are highly interchangeable, suggesting more flexibility in clinical implementation.

KW - Imaging

KW - MRI

KW - Normative data

KW - Subcortical brain volume

UR - http://www.scopus.com/inward/record.url?scp=85071529121&partnerID=8YFLogxK

U2 - 10.1016/j.neurobiolaging.2019.07.008

DO - 10.1016/j.neurobiolaging.2019.07.008

M3 - Article

VL - 84

SP - 9

EP - 16

JO - Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology

JF - Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology

SN - 0197-4580

ER -

ID: 56897399