1. 2019
  2. Multiplexed Cas9 targeting reveals genomic location effects and gRNA-based staggered breaks influencing mutation efficiency

    Gisler, S., *(joint 1st), Gonçalves, J. P., *(joint 1st), Akhtar, W., *(joint 1st), de Jong, J., Pindyurin, A. V., Wessels, L. & van Lohuizen, M., Mar 2019, (Accepted/In press) In : Nature Communications.

    Research output: Contribution to journalArticleScientificpeer-review

  3. Centenarian controls increase variant effect sizes by an average twofold in an extreme case–extreme control analysis of Alzheimer’s disease

    Tesi, N., van der Lee, S. J., Hulsman, M., Jansen, I. E., Stringa, N., van Schoor, N., Meijers-Heijboer, H., Reinders, M. J. T., Holstege, H. & More Authors, 2019, In : European Journal of Human Genetics. 27, 2, p. 244-253 10 p.

    Research output: Contribution to journalArticleScientificpeer-review

  4. Computational analysis of copy number profiles of tumors

    Van Dyk, E., 2019, 170 p.

    Research output: ThesisDissertation (TU Delft)Scientific

  5. Optimized ChIP-seq method facilitates transcription factor profiling in human tumors

    Singh, A. A., Schuurman, K., Nevedomskaya, E., Stelloo, S., Linder, S., Droog, M., Kim, Y., Sanders, J., van der Poel, H., Bergman, A. M., Wessels, L. F. A. & Zwart, W., 2019, In : Life Science Alliance. 2, 1, p. 1-12 12 p., e201800115.

    Research output: Contribution to journalArticleScientificpeer-review

  6. 2018
  7. Transcriptomics and transposon mutagenesis identify multiple mechanisms of resistance to the FGFR inhibitor AZD4547

    Kas, S. M., De Ruiter, J. R., Schipper, K., Schut, E., Bombardelli, L., Wientjens, E., Drenth, A. P., De Korte-Grimmerink, R., Mahakena, S., Phillips, C., Smith, P. D., Klarenbeek, S., Van De Wetering, K., Berns, A., Wessels, L. F. A. & Jonkers, J., 1 Oct 2018, In : Cancer Research. 78, 19, p. 5668-5679 12 p.

    Research output: Contribution to journalArticleScientificpeer-review

  8. Automatic analysis of human social behavior in - the - wild using multimodal streams

    Cabrera Quiros, L., 27 Sep 2018, 147 p.

    Research output: ThesisDissertation (TU Delft)Scientific

  9. How metabolic state may regulate fear: Presence of metabolic receptors in the fear circuitry

    Koorneef, L. L., Bogaards, M., Reinders, M. J. T., Meijer, O. C. & Mahfouz, A., 27 Aug 2018, In : Frontiers in Neuroscience. 12, 594.

    Research output: Contribution to journalArticleScientificpeer-review

  10. Nucleus-specific expression in the multinuclear mushroom-forming fungus Agaricus bisporus reveals different nuclear regulatory programs

    Gehrmann, T., Pelkmans, J. F., Ohm, R. A., Vos, A. M., Sonnenberg, A. S. M., Baars, J. J. P., Wösten, H. A. B., Reinders, M. J. T. & Abeel, T., 24 Apr 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 17, p. 4429-4434 6 p.

    Research output: Contribution to journalArticleScientificpeer-review

  11. A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

    Sachs, N., de Ligt, J., Kopper, O., Gogola, E., Bounova, G., Weeber, F., Balgobind, A. V., Wind, K., Gracanin, A., Wessels, L. & More Authors, 11 Jan 2018, In : Cell. 172, 1-2, p. 373-386.e10

    Research output: Contribution to journalArticleScientificpeer-review

  12. A rare genetic variant in the PLCG2 gene is associated with a reduced risk of all major types of dementia and an increased risk to reach an extremely old age

    van der Lee, S. J., Jansen, I. E., Pletnikova, O., Blauwendraat, C., Hulsman, M., Dalmasso, M. C., Kawalia, A., Ramirez, A., van der Flier, W. M., Scheltens, P., Reinders, M. & More Authors, 2018, In : Alzheimer's & Dementia. 14, 7, p. 1648-1649 2 p.

    Research output: Contribution to journalArticleScientificpeer-review

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