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Synthetic Biology for Multiscale Designed Biomimetic Assemblies : From Designed Self-Assembling Biopolymers to Bacterial Bioprinting. / Majerle, Andreja; Schmieden, Dominik T.; Jerala, Roman; Meyer, Anne S.

In: Biochemistry, Vol. 58, No. 16, 2019, p. 2095-2104.

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Majerle, Andreja ; Schmieden, Dominik T. ; Jerala, Roman ; Meyer, Anne S. / Synthetic Biology for Multiscale Designed Biomimetic Assemblies : From Designed Self-Assembling Biopolymers to Bacterial Bioprinting. In: Biochemistry. 2019 ; Vol. 58, No. 16. pp. 2095-2104.

BibTeX

@article{41ba991f88f04d809bb5fe2b5147d83e,
title = "Synthetic Biology for Multiscale Designed Biomimetic Assemblies: From Designed Self-Assembling Biopolymers to Bacterial Bioprinting",
abstract = "Nature is based on complex self-assembling systems that span from the nanoscale to the macroscale. We have already begun to design biomimetic systems with properties that have not evolved in nature, based on designed molecular interactions and regulation of biological systems. Synthetic biology is based on the principle of modularity, repurposing diverse building modules to design new types of molecular and cellular assemblies. While we are currently able to use techniques from synthetic biology to design self-assembling molecules and re-engineer functional cells, we still need to use guided assembly to construct biological assemblies at the macroscale. We review the recent strategies for designing biological systems ranging from molecular assemblies based on self-assembly of (poly)peptides to the guided assembly of patterned bacteria, spanning 7 orders of magnitude.",
author = "Andreja Majerle and Schmieden, {Dominik T.} and Roman Jerala and Meyer, {Anne S.}",
note = "Accepted Author Manuscript",
year = "2019",
doi = "10.1021/acs.biochem.8b00922",
language = "English",
volume = "58",
pages = "2095--2104",
journal = "Biochemistry",
issn = "0006-2960",
publisher = "American Chemical Society (ACS)",
number = "16",

}

RIS

TY - JOUR

T1 - Synthetic Biology for Multiscale Designed Biomimetic Assemblies

T2 - Biochemistry

AU - Majerle, Andreja

AU - Schmieden, Dominik T.

AU - Jerala, Roman

AU - Meyer, Anne S.

N1 - Accepted Author Manuscript

PY - 2019

Y1 - 2019

N2 - Nature is based on complex self-assembling systems that span from the nanoscale to the macroscale. We have already begun to design biomimetic systems with properties that have not evolved in nature, based on designed molecular interactions and regulation of biological systems. Synthetic biology is based on the principle of modularity, repurposing diverse building modules to design new types of molecular and cellular assemblies. While we are currently able to use techniques from synthetic biology to design self-assembling molecules and re-engineer functional cells, we still need to use guided assembly to construct biological assemblies at the macroscale. We review the recent strategies for designing biological systems ranging from molecular assemblies based on self-assembly of (poly)peptides to the guided assembly of patterned bacteria, spanning 7 orders of magnitude.

AB - Nature is based on complex self-assembling systems that span from the nanoscale to the macroscale. We have already begun to design biomimetic systems with properties that have not evolved in nature, based on designed molecular interactions and regulation of biological systems. Synthetic biology is based on the principle of modularity, repurposing diverse building modules to design new types of molecular and cellular assemblies. While we are currently able to use techniques from synthetic biology to design self-assembling molecules and re-engineer functional cells, we still need to use guided assembly to construct biological assemblies at the macroscale. We review the recent strategies for designing biological systems ranging from molecular assemblies based on self-assembly of (poly)peptides to the guided assembly of patterned bacteria, spanning 7 orders of magnitude.

UR - http://www.scopus.com/inward/record.url?scp=85064840269&partnerID=8YFLogxK

U2 - 10.1021/acs.biochem.8b00922

DO - 10.1021/acs.biochem.8b00922

M3 - Article

VL - 58

SP - 2095

EP - 2104

JO - Biochemistry

JF - Biochemistry

SN - 0006-2960

IS - 16

ER -

ID: 53623743