The effect of non-contrast CT slice thickness on thrombus density and perviousness assessment

M. L. Tolhuisen*, J. Enthoven, Emilie M M Santos, W. J. Niessen, L. F.M. Beenen, D. W.J. Dippel, A. van der Lugt, W. H. van Zwam, Y. B.W.E.M. Roos, R. J. van Oostenbrugge, More Authors

*Corresponding author for this work

    Research output: Chapter in Book/Conference proceedings/Edited volumeConference contributionScientificpeer-review

    5 Citations (Scopus)

    Abstract

    [Background] It is expected that thrombus density and perviousness measurements are dependent on CT slice thickness, because density values are blurred in thicker slices. This study quantifies the effect of slice thickness on thrombus density and perviousness measurements. [Methods] Thrombus density and perviousness measurements were performed in 50 patients for varying slice thicknesses, using a manual and semi-automated technique. Linear regression was performed to determine the dependence of density measurements on slice thickness. Paired t-tests were used to test for differences in density and perviousness measures for varying slice thickness. [Results] Thrombus density decreased for increasing slice thickness with approximately 2HU per mm. Perviousness measurements were significantly higher for thick slice compared to thin slice NCCT. [Conclusion] Thick slice NCCT scans result in an underestimation of thrombus density and overestimation of thrombus perviousness.

    Original languageEnglish
    Title of host publicationMolecular Imaging, Reconstruction and Analysis of Moving Body Organs, and Stroke Imaging and Treatment - 5th International Workshop, CMMI 2017 2nd International Workshop, RAMBO 2017 and 1st International Workshop, SWITCH 2017 Held in Conjunction with MICCAI 2017, Proceedings
    EditorsJ. Cardoso, T. Arbel, F. Gao
    PublisherSpringer
    Pages168-175
    Volume10555 LNCS
    ISBN (Print)9783319675633
    DOIs
    Publication statusPublished - 2017
    Event5th International Workshop on Computational Methods for Molecular Imaging, CMMI 2017, 2nd International Workshop on Reconstruction and Analysis of Moving Body Organs, RAMBO 2017 and 1st International Stroke Workshop on Imaging and Treatment Challenges, SWITCH 2017 held in Conjunction with 20th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2017 - Quebec City, Canada
    Duration: 14 Sept 201714 Sept 2017

    Publication series

    NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
    Volume10555 LNCS
    ISSN (Print)03029743
    ISSN (Electronic)16113349

    Conference

    Conference5th International Workshop on Computational Methods for Molecular Imaging, CMMI 2017, 2nd International Workshop on Reconstruction and Analysis of Moving Body Organs, RAMBO 2017 and 1st International Stroke Workshop on Imaging and Treatment Challenges, SWITCH 2017 held in Conjunction with 20th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2017
    Country/TerritoryCanada
    CityQuebec City
    Period14/09/1714/09/17

    Keywords

    • CT
    • Ischemic stroke
    • Slice thickness
    • Thrombus density
    • Thrombus perviousness

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