• Francisco R. Fortea-Pérez
  • Marta Mon
  • Jesús Ferrando-Soria
  • Mercedes Boronat
  • Antonio Leyva-Pérez
  • Avelino Corma
  • Juan Manuel Herrera
  • Dmitrii Osadchii
  • Jorge Gascon
  • Donatella Armentano
  • Emilio Pardo

The development of catalysts able to assist industrially important chemical processes is a topic of high importance. In view of the catalytic capabilities of small metal clusters, research efforts are being focused on the synthesis of novel catalysts bearing such active sites. Here we report a heterogeneous catalyst consisting of Pd4 clusters with mixed-valence 0/+1 oxidation states, stabilized and homogeneously organized within the walls of a metal-organic framework (MOF). The resulting solid catalyst outperforms state-of-the-art metal catalysts in carbene-mediated reactions of diazoacetates, with high yields (>90%) and turnover numbers (up to 100,000). In addition, the MOF-supported Pd4 clusters retain their catalytic activity in repeated batch and flow reactions (>20 cycles). Our findings demonstrate how this synthetic approach may now instruct the future design of heterogeneous catalysts with advantageous reaction capabilities for other important processes.

Original languageEnglish
Pages (from-to)760-766
Number of pages7
JournalNature Materials
Issue number7
Publication statusPublished - 1 Jul 2017

ID: 21566055