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White-matter microstructure and hearing acuity in older adults : a population-based cross-sectional DTI study. / Rigters, Stephanie C.; Cremers, Lotte G M; Ikram, M. Arfan; van der Schroeff, Marc P.; De Groot, Marius; Roshchupkin, Gennady V.; Niessen, Wiro J.N.; Baatenburg de Jong, Robert J.; Goedegebure, André; Vernooij, Meike W.

In: Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology, Vol. 61, 01.01.2018, p. 124-131.

Research output: Contribution to journalArticleScientificpeer-review

Harvard

Rigters, SC, Cremers, LGM, Ikram, MA, van der Schroeff, MP, De Groot, M, Roshchupkin, GV, Niessen, WJN, Baatenburg de Jong, RJ, Goedegebure, A & Vernooij, MW 2018, 'White-matter microstructure and hearing acuity in older adults: a population-based cross-sectional DTI study' Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology, vol. 61, pp. 124-131. https://doi.org/10.1016/j.neurobiolaging.2017.09.018

APA

Rigters, S. C., Cremers, L. G. M., Ikram, M. A., van der Schroeff, M. P., De Groot, M., Roshchupkin, G. V., ... Vernooij, M. W. (2018). White-matter microstructure and hearing acuity in older adults: a population-based cross-sectional DTI study. Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology, 61, 124-131. https://doi.org/10.1016/j.neurobiolaging.2017.09.018

Vancouver

Rigters SC, Cremers LGM, Ikram MA, van der Schroeff MP, De Groot M, Roshchupkin GV et al. White-matter microstructure and hearing acuity in older adults: a population-based cross-sectional DTI study. Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology. 2018 Jan 1;61:124-131. https://doi.org/10.1016/j.neurobiolaging.2017.09.018

Author

Rigters, Stephanie C. ; Cremers, Lotte G M ; Ikram, M. Arfan ; van der Schroeff, Marc P. ; De Groot, Marius ; Roshchupkin, Gennady V. ; Niessen, Wiro J.N. ; Baatenburg de Jong, Robert J. ; Goedegebure, André ; Vernooij, Meike W. / White-matter microstructure and hearing acuity in older adults : a population-based cross-sectional DTI study. In: Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology. 2018 ; Vol. 61. pp. 124-131.

BibTeX

@article{3bb8d36f2c7a4089aa3e86ae3ed31e47,
title = "White-matter microstructure and hearing acuity in older adults: a population-based cross-sectional DTI study",
abstract = "To study the relation between the microstructure of white matter in the brain and hearing function in older adults we carried out a population-based, cross-sectional study. In 2562 participants of the Rotterdam Study, we conducted diffusion tensor imaging to determine the microstructure of the white-matter tracts. We performed pure-tone audiogram and digit-in-noise tests to quantify hearing acuity. Poorer white-matter microstructure, especially in the association tracts, was related to poorer hearing acuity. After differentiating the separate white-matter tracts in the left and right hemisphere, poorer white-matter microstructure in the right superior longitudinal fasciculus and the right uncinate fasciculus remained significantly associated with worse hearing. These associations did not significantly differ between middle-aged (51–69 years old) and older (70–100 years old) participants. Progressing age was thus not found to be an effect modifier. In a voxel-based analysis no voxels in the white matter were significantly associated with hearing impairment.",
keywords = "Age-related hearing impairment, DTI, Hearing acuity, Pure-tone audiogram, Superior longitudinal fasciculus, Uncinate fasciculus, Voxel-based analysis, White-matter tract",
author = "Rigters, {Stephanie C.} and Cremers, {Lotte G M} and Ikram, {M. Arfan} and {van der Schroeff}, {Marc P.} and {De Groot}, Marius and Roshchupkin, {Gennady V.} and Niessen, {Wiro J.N.} and {Baatenburg de Jong}, {Robert J.} and Andr{\'e} Goedegebure and Vernooij, {Meike W.}",
year = "2018",
month = "1",
day = "1",
doi = "10.1016/j.neurobiolaging.2017.09.018",
language = "English",
volume = "61",
pages = "124--131",
journal = "Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology",
issn = "0197-4580",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - White-matter microstructure and hearing acuity in older adults

T2 - Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology

AU - Rigters, Stephanie C.

AU - Cremers, Lotte G M

AU - Ikram, M. Arfan

AU - van der Schroeff, Marc P.

AU - De Groot, Marius

AU - Roshchupkin, Gennady V.

AU - Niessen, Wiro J.N.

AU - Baatenburg de Jong, Robert J.

AU - Goedegebure, André

AU - Vernooij, Meike W.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - To study the relation between the microstructure of white matter in the brain and hearing function in older adults we carried out a population-based, cross-sectional study. In 2562 participants of the Rotterdam Study, we conducted diffusion tensor imaging to determine the microstructure of the white-matter tracts. We performed pure-tone audiogram and digit-in-noise tests to quantify hearing acuity. Poorer white-matter microstructure, especially in the association tracts, was related to poorer hearing acuity. After differentiating the separate white-matter tracts in the left and right hemisphere, poorer white-matter microstructure in the right superior longitudinal fasciculus and the right uncinate fasciculus remained significantly associated with worse hearing. These associations did not significantly differ between middle-aged (51–69 years old) and older (70–100 years old) participants. Progressing age was thus not found to be an effect modifier. In a voxel-based analysis no voxels in the white matter were significantly associated with hearing impairment.

AB - To study the relation between the microstructure of white matter in the brain and hearing function in older adults we carried out a population-based, cross-sectional study. In 2562 participants of the Rotterdam Study, we conducted diffusion tensor imaging to determine the microstructure of the white-matter tracts. We performed pure-tone audiogram and digit-in-noise tests to quantify hearing acuity. Poorer white-matter microstructure, especially in the association tracts, was related to poorer hearing acuity. After differentiating the separate white-matter tracts in the left and right hemisphere, poorer white-matter microstructure in the right superior longitudinal fasciculus and the right uncinate fasciculus remained significantly associated with worse hearing. These associations did not significantly differ between middle-aged (51–69 years old) and older (70–100 years old) participants. Progressing age was thus not found to be an effect modifier. In a voxel-based analysis no voxels in the white matter were significantly associated with hearing impairment.

KW - Age-related hearing impairment

KW - DTI

KW - Hearing acuity

KW - Pure-tone audiogram

KW - Superior longitudinal fasciculus

KW - Uncinate fasciculus

KW - Voxel-based analysis

KW - White-matter tract

UR - http://www.scopus.com/inward/record.url?scp=85032859257&partnerID=8YFLogxK

U2 - 10.1016/j.neurobiolaging.2017.09.018

DO - 10.1016/j.neurobiolaging.2017.09.018

M3 - Article

VL - 61

SP - 124

EP - 131

JO - Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology

JF - Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology

SN - 0197-4580

ER -

ID: 33423923